show Abstracthide AbstractGossypol is a sesquiterpene produced by cotton plant and is toxic to organisms. Oxycarenus laetus is a pest of cotton that is not affected by the toxicity of gossypol. Here, we have performed transcriptome sequencing of O. laetus fed on (1) Abutilon indicum (no-gossypol), Gossypium hirsutum (natural gossypol) and seeds of G. hirsutum treated with gossypol to identify genes differentially expressed upon exposure to gossypol.